TS 2003 and Excel 2000 problem

We have TS server running Window server 2003 R2, we also run MS Office

2000. We are having a problem where the user has excel open on there

desktop and working quite happily and then suddenly excel with just

disappear, no error message appear on screen, now error message are shown

in the event log, infact there is no trace of anything having happened.

Office 2000 is update with all available updates. Our user base run a mix

of PC with MS RDP client and Thin Client Terminals. The disappearing

Excel does not show any preference to PC or terminal, large multi page

spreadsheet or a few rows on a single page.

Any suggestions??

Tim